Safety and Effectiveness of Cord Blood Stem Cell Infusion for the Treatment of Cerebral Palsy in Children

Department of Neurology Research
1120 Fifteenth Street
Augusta, Georgia 30912

Mission:

The purpose of this program is to use adult stem cells to treat brain injuries resulting from stroke and decreased blood flow and oxygen. We are currently conducting studies in animals designed to translate the scientific aspects of stem cells into their clinical use in patients. Our work applies to the treatment of both adults and children. These injuries are often severe and result in longstanding disability. We hope to treat these injuries by transplanting cells derived from bone marrow, thereby improving the patients' quality of life.
Our research is focused in the long term on the treatment of neurological illnesses such as stroke, cerebral palsy, and Parkinson's disease. Our current focus is on stroke and neonatal hypoxic-ischemic injury.

Chairman: David Hess, MD

Vice-Chairman: James Carroll, MD

Drs. Hess and Carroll have experience in clinical child neurology, laboratory assessment of adult stem cells in animal models, and design of clinical trials.

Background:

David Hess, MD, Chairman, Adult Stem Cell Laboratory, Department of Neurology Research
Education/Training:
B.A., The Johns Hopkins University, Baltimore, Maryland, 1979
M.D., University of Maryland School of Medicine, Baltimore, Maryland, 1983
Internship, Internal Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania, 1984
Residency, Internal Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania, 1986
Residency, Neurology, Medical College of Georgia, Augusta, Georgia, 1989

James Carroll, MD, Vice- Chairman, Adult Stem Cell Laboratory, Department of Neurology Research
Education/Training:
B.S., University of Louisville, Louisville, Kentucky, 1966
M.D., University of Louisville, Louisville, Kentucky, 1969
Residency, Pediatrics, University of Louisville Children's Hospital, 1971
Fellowship Pediatric Neurology, University of Colorado, 1976
Fellowship, Neuromuscular Disease, Washington University, St. Louis, 1977
Research Fellow, NDA, Washington University, St. Louis, 1978
Both have experience in clinical child neurology, laboratory assessment of adult stem cells in animal models, and design of clinical trials.

Major Accomplishments:

Successful animal testing multipotent adult progenitor cells in rat models of stroke and neonatal hypoxic-ischemic injury.

Current Projects:

1.Adult Stem Cells Aid Recovery in Animal Model of Cerebral Palsy
2.Transplantation of Bone Marrow-derived Cells for the Treatment of Stroke
3.Transplanting Stem Cell into Rats Following Stroke
Initial results show that adult stem cell transplantation significantly improves the behavioral outcome in adult stroke and neonatal hypoxic-ischemic injury in rats.

Clinical Trials:

Please contact Dr. James Carroll at This e-mail address is being protected from spambots. You need JavaScript enabled to view it or call 1-706-721-3371 if you are interested in our clinical trial or if you would like some more information.