About The ASCR Network
The Adult Stem Cell Research (ASCR) Network is an internet-based project of the Cell Therapy Foundation designed to be a well-maintained and reliable source of information for physicians and the public regarding adult stem cell research. ASCR seeks to disseminate the latest scientific news in the adult stem cell arena, identify leading researchers in the field, and locate key clinical trials in order to help patients and research unite in a beneficial and timely manner.
Additionally, a future goal of the ASCR Network is to be a community of education and collaboration where news, ideas and research will merge in real-time with the aim of translating the best therapeutic practices to the patient in the most efficient, lay-friendly way possible.
While much progress has been made in the last few years, many therapies are still experimental and/or not ready for use in human trials. The Cell Therapy Foundation and ASCR Network seek to breach that gap by information sharing and collaboration. Consider partnering with us in this cause. Your vital donation will help support our efforts to transform a mere experiment in the lab today into a cure for thousands of patients tomorrow! Click here to donate.
ADULT STEM CELL NEWS
Find links below to the latest news and developments
in the adult stem cell sector from around the world.
RESEARCH WATCH: Heart Health
April 24, 2014
Researchers at The Ohio State University propose that it may be possible to understand key factors of cardiovascular health without the need to identify blood adult stem cells.
By analyzing the whole nonpurified cell population of the blood, they determined that they could identify the cells that are assisting in the same way that endothelial progenitor cell would. They looked at gene activity patterns in these general cells that circulate in the blood and determined that many different types may help in the regenerative effects of blood vessel repair.
RESEARCH WATCH: Growing A New Esophagus
April 24, 2014
Researchers at Karolinska Institutet in Sweden have developed a method to successfully grow and transplant natural esophagus organs into rats.
Collaborating with teams around the world (including the U.S.), the Karolinska team started with esophagi that were removed from rats and then they cleared all the cells; this process leaves only the “scaffold” behind (which retains the structural, mechanical and chemical properties of the original organ).
Expansion of hMSCs using synthetic microcarriers in xeno-free medium looks promising
April 18, 2014
An article from last month reviews an attempt at long-term expansion of human mesenchymal stem cells (hMSCs) using synthetic microcarriers. Mesenchymal stem cells are currently used to treat a variety of diseases, including lung injuries and heart disease. This experiment yielded promising results that would have a positive impact on the growing need for large-scale expansion of hMSCs for therapeutic purposes.
Results from Cytori's PRECISE trial indicate benefits from administration of Cytori Cell Therapy
April 14, 2014
An April 14 announcement from Cytori Therapeutics indicates the favorable results from their PRECISE clinical trial will be published in an upcoming issues of American Heart Journal. This 36 month trial was a first-in-man trial involving injection of adipose stem cells into myocardial tissue for heart disease and 27 patients participated.
Cytori’s therapeutic product, Cytori Cell Therapy, is a mixed population of adipose-derived stem cells, known collectively as ADRCs, and the stem cells were injected directly into damaged, but still viable, areas of the heart in 21 of the patients. At both 6 and 18 months, the results show that exercise capacity was sustained in the treated group, but went down in the placebo group, and also indicated that ADRC’s may help prevent scar tissue from increasing after myocardial infarctions.
* Designates sites with available clinical trials.
- * Adult Stem Cell Laboratory, Medical College of Georgia
- * Feinberg Cardiovascular Research Institute - Northwestern University, Chicago, IL
- * Indiana Center for Vascular Biology and Medicine, Laboratories - Indianapolis, IN
- * Regenerative Medicine Institute, Mexico
- * Stem Cell Center at Texas Heart Institute - Houston, TX
- * Adipose Stem Cell Center, University of Pittsburgh - Pittsburgh, PA
- Adipose Tissue Plasticity - Toulouse France
- Adult Stem Cell Laboratory - Seoul, South Korea
- Adult Stem Cell Research Ctr, Seoul National University - Seoul, South Korea
- The Cardiovascular Research Institute - Washington, DC
- * Center for Cardiovascular Cell Therapy - Louisville, KY
- * Division of Clinical Immunology and Transfusional Medicine - Stockholm, Sweden
- Excellion Biomedical Services - Petropolis, Rio de Janeiro
- * Interdisciplinary Stem Cell Institute/UM Med - Miami, FL
- Institute of Cell and Molecular Science - London, England
- Kolonin Lab - Centre for Stem Cell Research - Houston, TX
- Laboratory for Stem Cell Injury - Charleston, SC
- LIT - Laboratory of Transplantation Immunobiology - Sao Paulo, Brazil
- * Minneapolis Heart Institute Foundation - Minneapolis, MN
- * Molecular Cardiology Laboratory - ThoraxCenter - Rotterdam, Netherlands
- National Centre for Adult Stem Cell Research at Griffith University - Nathan Queensland, Australia
- Naviaux Lab - The Mitochondrial and Metabolic Disease Center - San Diego, CA
- Oklahoma Center for Adult Stem Cell Research (OCASCR) - Oklahoma City, OK
- * Penn Lab - Cleveland Clinic - Cleveland, OH
- Prantl Laboratory - Center for Adult Stem Cell Research - Regensburg, Germany
- Research & Development Unit - National Heart Centre, Singapore
- RhinoCyte™, Inc. - Louisville, KY
- Scandurro Research Laboratory - New Orleans, LA
- Simari Lab - Mayo Clinic - Rochester, MN
- * Skeletal Tissue Engineering Group - Amsterdam
- * Skeletal Research Center, Case Western Reserve University - Cleveland, OH
- Stem Cell Biology Laboratory, Pennington Biomedical Research Center - Baton Rouge, LA
- Stem Cell Biology and Cell Therapy Laboratory - Philadelphia, PA
- Stem Cell Research Center - Pittsburgh, PA
- Stem Cell Research Center - Taipei, Taiwan
- Yoder Laboratory - Indianapolis, IN
- * Wake Forest Institute of Regenerative Medicine - Winston-Salem, NC