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The Adult Stem Cell Research (ASCR) Network is an Internet-based project of The Cell Therapy Foundation designed to be a well-maintained and reliable source of information for the public regarding adult stem cell research, as well as to be a community of practice and collaboration among fellow researchers. ASCR publishes the latest scientific news in the adult stem cell arena, identifies the leading researchers in the field, and locates key clinical trials; as well as connects the global community of adult stem cell researchers with one another.
Getting Started...
Available Clinical Trials
Multiple additional trials are presently ongoing – please contact Cell Therapy Foundation for additional information or specific inquiries.
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Empowering the Body to Fix Its Parts |
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By Samer Fakhri | May 15, 2012
Over the past few months, we have been flooded with emails from distressed parents asking whether their deaf child will be able to hear one day.
With each new email comes a poignant story about a child whose world is silent. It is estimated that hearing loss affects 11% of school age children and even mild loss may adversely influence school performance, cognitive development and language acquisition. The most common type of hearing loss, sensorineural, is the result of injury to the hair cells of the inner ear's Organ of Corti, most commonly due to infections, medication, noise and aging.
Hair cells are mechano-transducers which convert sound energy received from the outer and middle ear structures into an electrical signal which is then transmitted by the cochlear nerve to the brain. If enough of a human's 17,000 hair cells are damaged, then sufficient sound energy cannot be transmitted to the brain, and the result is hearing loss. While birds and reptiles replace damaged hair cells, mammals normally do not.
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Parcell Laboratories Honored as 2012 SBANE Innovation Award Winner |
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NEWTON, Mass., May 14, 2012 /PRNewswire via COMTEX/ -- Parcell Laboratories, a leading adult stem cell company based in Newton, MA, was awarded the prestigious 2012 Innovation Award by the Smaller Business Association of New England (SBANE). Parcell joins the select list of winning companies from the last 26 years whose innovations have delivered proven value to customers.
SBANE uses its highly competitive Innovation Awards program to showcase technology driven enterprises that are potentially "game changers" in their markets. Parcell's ELA® stem cell technology is a platform technology that has unlimited applications for tissue regeneration and is positioned to change the face of regenerative medicine. "We are honored to have been recognized by SBANE for our accomplishments and to be included among the roster of extremely successful companies that have been previous winners of the award," said Pamela Layton, the CEO of Parcell Laboratories. "The award is a testament to the dedication and tenacity of our terrific team." Past award winners include some of the most recognizable names in New England business, including Staples, Genzyme, Ben & Jerry's and Nantucket Nectars.
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Toothless No More – Researchers Using Stem Cells to Grow New Teeth |
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by David J. Hill
May 10th, 2012
It may be hard to remember what it was like to lose a tooth as a child, but many adults get an unpleasant reminder as they age when their teeth begin to fall out (even those who don't play hockey) and must consider dentures or dental implants. For years, researchers have investigated stem cells in an effort to grow teeth made for a person's own cells. Toward this end, endodontics professor Dr. Peter Murray and colleagues from the College of Dental Medicine at Nova Southeastern University (NSU) have developed methods to control adult stem cell growth toward generating dental tissue and "real" replacement teeth.
The NSU researchers' approach is to extract stem cells from oral tissue, such as inside a tooth itself, or from bone marrow. After being harvested, the cells are mounted to a polymer scaffold in the shape of the desired tooth. The polymer is the same material used in bioreabsorable sutures, so the scaffold eventually dissolves away. Teeth can be grown separately then inserted into a patient's mouth or the stem cells can be grown within the mouth reaching a full-sized tooth within a few months.
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Compassionate Use of Pluristem's PLX Cells Saves the Life of a Child after Bone Marrow Transplantation Failure |
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IM Injections of PLX Cells Causing a Dramatic Recovery of Blood Forming Cells
HAIFA, ISRAEL, May 9, 2012 - Pluristem Therapeutics, Inc. (NASDAQCM:PSTI; TASE:PLTR) today announced that a seven year-old girl suffering from an aplastic bone marrow whose condition was rapidly deteriorating is now experiencing a reversal of her condition with a significant increase in her red cells, white cells and platelets following the intramuscular injection of the company's PLacental eXpanded (PLX) cells. Aplastic bone marrow is a disease where the patient has no blood-forming hematopoietic stem cells in the bone marrow.
"With her body rejecting all possible treatment - and with no other options - we finally turned to Pluristem's PLX cells, which literally saved her life," said Professor Reuven Or, Director of Bone Marrow Transplantation, Cell Therapy and Transplantation Research Center at Hadassah Medical Center and the child's physician. "The results of this unique case indicate that PLX cells may be effective in treating other diseases that affect the bone marrow."
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* Designates sites with available clinical trials.
- * Adult Stem Cell Laboratory, Medical College of Georgia
- * Feinberg Cardiovascular Research Institute - Northwestern University, Chicago, IL
- * Indiana Center for Vascular Biology and Medicine, Laboratories - Indianapolis, IN
- * Regenerative Medicine Institute, Mexico
- * Stem Cell Center at Texas Heart Institute - Houston, TX
- Adipose Stem Cell Center, University of Pittsburgh - Pittsburgh, PA
- Adipose Tissue Plasticity - Toulouse France
- Adult Stem Cell Laboratory - Seoul, South Korea
- Adult Stem Cell Research Ctr, Seoul National University - Seoul, South Korea
- The Cardiovascular Research Institute - Washington, DC
- Center for Cardiovascular Cell Therapy - Louisville, KY
- Division of Clinical Immunology and Transfusional Medicine - Stockholm, Sweden
- Excellion Biomedical Services - Petropolis, Rio de Janeiro
- Interdisciplinary Stem Cell Institute/UM Med - Miami, FL
- Institute of Cell and Molecular Science - London, England
- Kolonin Lab - Centre for Stem Cell Research - Houston, TX
- Laboratory for Stem Cell Injury - Charleston, SC
- LIT - Laboratory of Transplantation Immunobiology - Sao Paulo, Brazil
- Minneapolis Heart Institute Foundation - Minneapolis, MN
- Molecular Cardiology Laboratory - ThoraxCenter - Rotterdam, Netherlands
- National Centre for Adult Stem Cell Research at Griffith University - Nathan Queensland, Australia
- Naviaux Lab - The Mitochondrial and Metabolic Disease Center - San Diego, CA
- Oklahoma Center for Adult Stem Cell Research (OCASCR) - Oklahoma City, OK
- Penn Lab - Cleveland Clinic - Cleveland, OH
- Prantl Laboratory - Center for Adult Stem Cell Research - Regensburg, Germany
- Research & Development Unit - National Heart Centre, Singapore
- RhinoCyte™, Inc. - Louisville, KY
- Scandurro Research Laboratory - New Orleans, LA
- Simari Lab - Mayo Clinic - Rochester, MN
- Skeletal Tissue Engineering Group - Amsterdam
- Skeletal Research Center, Case Western Reserve University - Cleveland, OH
- Stem Cell Biology Laboratory, Pennington Biomedical Research Center - Baton Rouge, LA
- Stem Cell Biology and Cell Therapy Laboratory - Philadelphia, PA
- Stem Cell Research Center - Pittsburgh, PA
- Stem Cell Research Center - Taipei, Taiwan
- Yoder Laboratory - Indianapolis, IN
- Wake Forest Institute of Regenerative Medicine - Winston-Salem, NC
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